Thursday, March 05, 2015

Medical Honey Gel is Safe Alternative Treatment for Chronically Discharging Open Mastoid Cavity

Treatment of Chronically Infected Open Mastoid Cavities with Medical Honey: A Randomized Controlled Trial

Otol Neurotol. 2015 Feb 28. [Epub ahead of print]

OBJECTIVE:

To investigate the efficacy of medical honey as topical treatment of chronically discharging open mastoid cavities in comparison with conventional eardrops.

STUDY DESIGN:

Single-center, prospective, randomized controlled, double-dose trial of 12 weeks.

PATIENTS AND INTERVENTION:

Twenty-eight patients diagnosed as having a chronically discharging open mastoid cavity underwent medical honey gel (intervention) or conventional eardrops (control) treatment. Treatment interventions were repeated after 4 weeks.

MAIN OUTCOME MEASURES:

Visual analogue scale of ear complaints, cavity inflammation, and bacterial infection.

RESULTS:

Most patients had a cavity with localized granulation. After treatment, inflammation score decreased in both groups (p < 0.05), with more pronounced inflammation-free cavities in the honey group. Honey treatment resulted in less discomfort (p < 0.001) and otorrhea (p < 0.001), even after correction for additional medication use (p < 0.05, p < 0.01). This decrease was not seen in the control group. Pain and itching did not change on treatment. Most cavities were infected with Pseudomonas species and Staphylococcus aureus. After treatment, a 23% increase of negative culture was seen with honey compared with 30% in the control group (nonsignificant). No serious adverse reactions were found.

CONCLUSION:

Medical honey gel is a safe alternative treatment option for patients with a chronically discharging open mastoid cavity and beneficial in reducing discomfort, otorrhea, and inflammation with a bactericidal effect.

Wednesday, March 04, 2015

Royal Jelly, Bee Pollen Used in Fertility Smoothie Recipe

Nourish Your Body With This Fertility Smoothie Recipe

Modern Mom

Something I have all my clients drink pre-pregnancy is my fertility smoothie. Not only does it taste AMAZING but also it does so many awesome things to enrich your body getting it ready for pregnancy. Everyday millions old cells die and millions are new cells are born. The anti-oxidants and greens in this smoothie help feed the new cells that are being birthed. The added supplements are to support fertility.  I know that it can be annoying and time consuming to take a ton of vitamins and supplements everyday but what I love about my smoothie is, you throw it all together in a blender and you are good to go.

Fertility Smoothie Recipe

Ingredients

  • Frozen mixed organic berries – You can buy fresh berries and freeze them)
  • Almond or rice milk  – You can also use organic milk if you choose)
  • Protein powder – Something natural and clean without a lot of additives or soy. Think whey.
  • 2 shots of wheat grass – You can use powder or fresh shots. I use a frozen one by Evergreen
  • Maca Root Powder
  • Acai berry
  • Mixed powdered greens
  • Royal Jelly *NOTE, if you are allergic to bees, do not use
  • Bee pollen *Again don’t use is you have a bee allergy
  • Liquid omegas – Read dose instructions on back of product
  • Mix all of this together in a blender. Depending on thickness, use as much milk as you want for the consistency you like...

Royal Jelly balances hormones, supports endocrine system , helps raise estrogen levels ( great for woman who have low estrogen ) , helps increase sperm quality and testosterone levels in men .

Bee Pollen has high levels of vitamins, natural aphrodisiac, Nourishes the ovaries, help produce healthy eggs, increases fertility, increases sperm count in men and balances menstrual cycle.

Tuesday, March 03, 2015

Propolis May Help Treat Cancer

Emerging Adjuvant Therapy for Cancer: Propolis and its Constituents

J Diet Suppl. 2015 Feb 27. [Epub ahead of print]

Propolis is a bee-metabolized resinous substance (bee glue) from plant sap and gums. It has been in usage as a healing agent since antiquity, yet has not garnered global popularity as a health promoter. Its biological effects, which range from antimicrobial, antioxidant, anti-inflammatory, antidiabetic, dermatoprotective, anti-allergic, laxative and immunomodulatory to anticancer, have been validated.

Propolis has shown efficacy against brain, head and neck, skin, breast, liver, pancreas, kidney, bladder, prostate, colon and blood cancers.

The inhibition of matrix metalloproteinases, anti-angiogenesis, prevention of metastasis, cell-cycle arrest, induction of apoptosis and moderation of the chemotherapy-induced deleterious side effects have been deduced as the key mechanisms of cancer manipulation. The components conferring antitumor potentials have been identified as caffeic acid phenethyl ester, chrysin, artepillin C, nemorosone, galangin, cardanol, etc. These compounds target various genetic and biochemical pathways of cancer progression. Depending on the botanical sources and the geographical origin, biological activities of propolis vary. Despite phenomenal development in cancer research, conventional therapy falls short in complete malignancy management.

The findings obtained so far build hope that propolis as a complementary medicine may address the lacunae. This review documents the recent advances and scope of amendement in cancer remediation with adequate emphasis on the mechanistic aspect of propolis.

Monday, March 02, 2015

Beekeepers invent device to collect honey without disturbing hive, funding target hit within seconds

ABC, 2/23/2015

A new device which allows beekeepers to extract honey without disturbing the hive is to go into full-scale production, after receiving overwhelming support from online crowdfunding.

Stuart Anderson and son Cedar, from northern New South Wales, invented the inbuilt extractor which collects fresh honey as it drips out through plastic tubes.

Their product, the Flow Hive, was officially launched in Canberra this morning, with an online campaign which raised its $70,000 target within seconds.

The campaign will be open to online funding pledges until April and has already received more than $1 million in donations from bee enthusiasts around the world...

Saturday, February 28, 2015

Honey Vinegar Syrup Fasting Insulin Level

Effect of honey vinegar syrup on blood sugar and lipid profile in healthy subjects

Int J Prev Med. 2014 Dec;5(12):1608-15.

BACKGROUND:

The impact of honey or vinegar on several metabolic abnormalities has been studied separately, a mixture of these two ingredients known as honey vinegar syrup (HVS) has not been investigated previously so far. The aim of this study was to assess the impact of HVS consumption (Iranian's traditional syrup) on glycemic parameters and lipid profiles in healthy individuals.

METHODS:

We conducted a 4-week, randomized, controlled, parallel study consisting of two groups of nonobese healthy volunteers. All subjects were asked to stay on their normal diet. Intervention group (n = 36) received a cup of HVS daily in the evening snack for 4-week (250 cc syrup contains 21.66 g honey vinegar). Assessments of fasting blood sugar (FBS), insulin, homeostasis model assessment of insulin resistance (HOMA-IR), total cholesterol (TC), triglyceride (TG), high-density lipoprotein cholesterol (HDL-C) and low-density lipoprotein cholesterol (LDL-C) were conducted at the baseline and after 4-week of study.

RESULTS:

We observed no significant effect of HVS on FBS, HOMA-IR, LDL-C and TG. A significant effect of HVS was found on increasing fasting insulin and HOMA-IR and reduction in TC level only in intervention group (Δ =3.39 P = 0.01, Δ =1.65 P = 0.03, Δ = -9.43 P = 0.005, respectively). Changes of FBS, TG and LDL-C were 1.83 mg/dl, -1.53 mg/dl and - 3.99 mg/dl respectively in the intervention group. These changes were not significant. An unfavorable and significant reduction in HDL-C level was also observed between two groups (Δ = -4.82 P < 0.001 in the intervention group).

CONCLUSIONS:

Honey vinegar syrup increased fasting insulin level and decreased TC level in the intervention group. HVS had an unfavorable effect on HDL-C level. Further prospective investigations are warranted to confirm these findings.

Friday, February 27, 2015

Bee Venom Face Mask

Redbrick, 2/25/2015

Our next treatment is causing a buzz on the beauty scene. We all know that Botox all too often leads to being tight-lipped, looking permanently shocked and being puffy faced as chemicals circulate the face in order to reduce the lines and wrinkles gained through life. Now there is a new trend emerging- bee venom, guaranteeing the same effects as botox without pain. Alternatively, why not try a lip-plumping bee venom lip gloss, guaranteed to leave you pouty! Some spas and beauty clinics use bees to actually sting you but now you can enjoy the ‘benefits’ of botox from your own home and from a jar- no not a honey jar! The venom is extracted from bees and mixed into a rich, creamy base. I think I’ll leave my beauty regime venom free for now - it all sounds too Wicked Witch like for my liking.

Thursday, February 26, 2015

Flow Hive Honey on Tap Directly From Your Beehive

What are Flow Frames?

“Flow™” is the name of our new invention that allows honey to be harvested directly from the hive without opening the hive and with little disturbance to the bees.  The Flow frames are the beehive frames that make this possible.

What is a Flow Hive?

A Flow Hive is our term for a standard beehive using a brood box with one or more Flow Supers for honey storage and extraction.  A honeybee hive is usually made up of two boxes; the brood box where the queen bee lays eggs, and the ‘super’ with honeycomb for the storage of honey.  A ‘Flow Super’ is a beehive box using Flow Frames that the bees store honey in.

How do the Flow Frames work?

The Flow frame consists of already partly formed honeycomb cells.  The bees complete the comb with their wax, fill the cells with honey and cap the cells as usual.  When you turn the tool, a bit like a tap, the cells split vertically inside the comb forming channels, allowing the honey to flow down to a sealed trough at the base of the frame and out of the hive, while the bees are practically undisturbed on the comb surface.

When the honey has finished draining, you turn the tap again in the upper slot which resets the comb into the original position and allows the bees to chew the wax capping away, and fill it with honey again.

Wednesday, February 25, 2015

New Zealand's Manuka Health to Launch Bioactive Supplement

Voxy, 2/24/2015

Manuka Health, one of New Zealand’s most successful and fastest growing honey brands, is preparing to unveil MGO Manuka Honey with CycloPower, an advanced natural bioactive supplement, at Expo West in California, the world’s largest trade show for the natural, organic and health products industry.

In what is a pioneering move for the Manuka Honey industry, Manuka Health is the first to have combined all natural CycloPower technology with the proven health benefits of genuine New Zealand Manuka Honey. When combined with active ingredients (such as the methylglyoxal molecules found in Manuka Honey), the naturally fibrous cyclodextrin molecules in CycloPower substantially elevate the beneficial activity of Manuka Honey, making it tens of times more potent against certain bacteria then the Manuka Honey of the same strength. MGO Manuka Honey with CycloPower is more stable, soluble and bioavailable for more efficient delivery over a longer period of time.

"CycloPower is a breakthrough natural bioactive booster for more highly effective supplementation," explains Dr Mike Durbin, Manuka Health’s General Manager of Wellness. "It is to natural healthcare what turbo is to cars - a way to get more performance without increasing the dose."...

Tuesday, February 24, 2015

Methylglyoxal Fibers as Antibacterial Wound Dressing

Investigation into the potential use of poly(vinyl alcohol)/methylglyoxal fibres as antibacterial wound dressing components

J Biomater Appl March 2015   vol. 29  no. 8  1193-1200

As problems of antibiotic resistance increase, a continuing need for effective bioactive wound dressings is anticipated for the treatment of infected chronic wounds. Naturally derived antibacterial agents, such as Manuka honey, consist of a mixture of compounds, more than one of which can influence antimicrobial potency.

The non-peroxide bacteriostatic properties of Manuka honey have been previously linked to the presence of methylglyoxal. The incorporation of methylglyoxal as a functional antibacterial additive during fibre production was explored as a potential route for manufacturing wound dressing components. Synthetic methylglyoxal and poly(vinyl alcohol) were fabricated into webs of sub-micron fibres by means of electrostatic spinning of an aqueous spinning solution. Composite fabrics were also produced by direct deposition of the poly(vinyl alcohol)–methylglyoxal fibres onto a preformed spunbonded nonwoven substrate. Attenuated total reflectance fourier transform infrared and proton nuclear magnetic resonance spectroscopies confirmed the presence of methylglyoxal within the resulting fibre structure.

The antibacterial activity of the fibres was studied using strains of Staphylococcus aureus and Escherichia coli. Strong antibacterial activity, as well as diffusion of methylglyoxal from the fibres was observed at a concentration of 1.55 mg/cm2.

Monday, February 23, 2015

Phenolic/H2O2-Induced Oxidative Stress Mechanism for Honey Antibacterial Action

Unraveling a mechanism of honey antibacterial action: Polyphenol/H2O2-induced oxidative effect on bacterial cell growth and on DNA degradation

Food Chem. 2012 Jul 15;133(2):329-36

Several compounds with antibacterial activities were identified in honey however, a mechanism by which they lead to bacterial growth inhibition and bacterial death remains still unknown. We recently found that honeys possess DNA degrading activity mediated by honey hydrogen peroxide and an unknown honey component(s).

Here we provide evidence that active honeys (MIC90 of 6.25-12.5% v/v) possessed significantly higher levels of phenolics (p < 0.02) of higher radical scavenging activities (p < 0.005) than honeys of average activity. Removal of H2O2 by catalase eliminated bacteriostatic activities caused by both phenolics and H2O2 suggesting that the growth inhibition resulted from the coupling chemistry between these compounds. Both phenolics and H2O2 were involved in DNA degradation by honeys. Treatment of plasmid DNA with H2O2 alone did not affect the DNA integrity but H2O2 removal from honey by catalase prevented DNA degradation. Polyphenols extracted from honeys degraded plasmid DNA in the presence of H2O2 and Cu(II) in the Fenton-type reaction. The extent of DNA degradation was inversely related to the polyphenol concentration in this system as well as in honeys. At low content, honey polyphenols exerted pro-oxidant activity damaging to DNA.

In conclusion, honey phenolics with pro-oxidant activities were necessary intermediates that conferred oxidative action of H2O2. Phenolic/H2O2-induced oxidative stress constituted the mechanism of honey bacteriostatic and DNA damaging activities.

Sunday, February 22, 2015

Royal Jelly May Help Delay Aging and Onset of Age-Related Disease

10-Hydroxy-2-decenoic Acid, the Major Lipid Component of Royal Jelly, Extends the Lifespan of Caenorhabditis elegans through Dietary Restriction and Target of Rapamycin Signaling

Journal of Aging Research
Volume 2015 (2015), Article ID 425261, 7 pages

Royal jelly (RJ) produced by honeybees has been reported to possess diverse health-beneficial properties and has been implicated to have a function in longevity across diverse species as well as honeybees. 10-Hydroxy-2-decenoic acid (10-HDA), the major lipid component of RJ produced by honeybees, was previously shown to increase the lifespan of Caenorhabditis elegans. The objective of this study is to elucidate signaling pathways that are involved in the lifespan extension by 10-HDA. 10-HDA further extended the lifespan of the daf-2 mutants, which exhibit long lifespan through reducing insulin-like signaling (ILS), indicating that 10-HDA extended lifespan independently of ILS. On the other hand, 10-HDA did not extend the lifespan of the eat-2 mutants, which show long lifespan through dietary restriction caused by a food-intake defect. This finding indicates that 10-HDA extends lifespan through dietary restriction signaling. We further found that 10-HDA did not extend the lifespan of the long-lived mutants in daf-15, which encodes Raptor, a target of rapamycin (TOR) components, indicating that 10-HDA shared some longevity control mechanisms with TOR signaling. Additionally, 10-HDA was found to confer tolerance against thermal and oxidative stress. 10-HDA increases longevity not through ILS but through dietary restriction and TOR signaling in C. elegans...

Conclusions

The present study indicates that 10-HDA extends lifespan of C. elegans not via ILS but via dietary restriction and the TOR signaling. It may be possible that 10-HDA contained in RJ which is widely taken by human as a health food could be used as nutraceutical intervention aimed at mTOR inhibition to delay aging and the onset of age-related diseases.

Saturday, February 21, 2015

Indian Apis Dorsata Bee Venom May Help Treat Arthritis Pain and Inflammation

Evaluation of anti-inflammatory, anti-nociceptive, and anti-arthritic activities of Indian Apis dorsata bee venom in experimental animals: biochemical, histological, and radiological assessment

Immunopharmacol Immunotoxicol. 2015 Feb 18:1-14

Traditionally venoms are used from thousands of years to treat pain, inflammation, and arthritis. In Ayurveda "Suchika Voron" and "Shodhona" were practiced against pain. In the present study, venom composition of the Indian honeybee Apis florea (AF), Apis dorsata (AD), and Apis cerana indica (AC) were analyzed using electrophoresis (SDS-PAGE).

This venom analysis was used to shed light upon the correlation in structure and the venom composition among the three species in Indian fields. Among the three species, Indian Apis dorsata bee venom (ADBV) is evaluated for an anti-inflammatory, anti-nociceptive activity, and antiarthritic activity in different animal models.

The effect of ADBV is revealed for its anti-arthritic activity in the FCA- and CIA-induced arthritis model in male Wistar rats. The immunosuppressant action of ADBV was studied by hemagglutination antibody titer.

It has been found that ADBV possesses anti-inflammatory and antinociceptive activities. In FCA- and CIA-induced arthritis, ADBV able to decrease rheumatoid factor, pain perception parameters, C-reactive protein, erythrocytes sedimentation rate, urinary hydroxyproline, serum transaminase level, and serum nitric oxide level when compared with diseased control arthritic rats. IL-6, TNF-α level was found to be decrease by ADBV treatment in collagen induced arthritis model.

Thus this study confirmed the scientific validation behind utilization of venom in Indian Apis dorsata bees in arthritis and inflammatory diseases which has been not reported till date.


Friday, February 20, 2015

How Queen Bees Suppress the Rest

(Feb. 18, 2015) - Researchers have identified the compounds present in queen manibular pheromone (QMP) that suppress ovary activation in ordinary worker bees. Their results, published in the Journal of Insect Physiology, could be used to help beekeepers control hive fertility. QMP is a group of (at least) five active compounds produced by queen honey bees.

Although the pheromone is known to aid queen control of the colony and colony cohesion, the effects of individual QMP components have never been tested to determine their effects on the reproductive physiology of Apis cerana workers. Prof. Tan Ken of Xishuangbanna Tropical Botanical Garden (XTBG) of Chinese Academy of Sciences and his colleagues conducted a study to provide groups of queenless A. cerana workers with individual QMP components in their food and determine which of the components are capable of suppressing ovary activation.

The researchers fed one queen equivalent of each of the major components of A. cerana QMP to groups of worker bees twice a day until the workers were ten days old. Half of the cages were also provided with ten percent royal jelly in the food…


Thursday, February 19, 2015

Bee Venom Therapy's Popularity Growing in India

State Apitherapy attracts huge crowd at national festival

Tseminyu, February 18 (MExN): A five-member team from Nagaland participated in the National Tribal Festival organised by the Ministry of Tribal Affairs, Government of India at Central Park, Connaught Place and Indira Gandhi National Centre for Arts, New Delhi from February 13 to 18.

The team from Healing Home of Teregonyu Village of Tseminyu Sub-division under Kohima District, who were facilitated and supported by the Nagaland Beekeeping and Honey Mission (NBHM), participated in the festival for ‘demonstration and treatment of various ailments and sicknesses of people through Apitherapy by use of bee venom.’

The Nagaland Apitherapy Stall attracted the attention of the Capital crowd; thousands of people were tested or treated and many experienced instant healing through the therapy by Lily Tep and her team, a press release stated. The participants from across the country highly demanded for Bee Venom Apitherapy Centre to be established in the Capital Delhi, said the press release...